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    50MG/TAB * 24TAB

    Clomiphene is a racemic mixture consisting of zuclomiphene (~38%) and enclomiphene (~62%), each with distinct pharmacologic properties. Clomiphene acts at the level of the hypothalamus, occupying cell surface and intracellular estrogen receptors (ERs) for longer durations than estrogen. This interferes with receptor recycling, effectively depleting hypothalamic ERs and inhibiting normal estrogenic negative feedback. Impairment of the feedback signal results in increased pulsatile GnRH secretion from the hypothalamus and subsequent pituitary gonadotropin (FSH, LH) release, causing growth of the ovarian follicle, followed by follicular rupture (ASRM 2013; Dickey, 1996).

    Readily absorbed.

    Hepatic; undergoes enterohepatic recirculation (Goldstein 2000).

    Time to Peak
    ~6 hours (Goldstein 2000).

    Half-Life Elimination
    ~5 days (Goldstein 2000).

    Detection Time
    ~60 days.

    • Availability: In Stock
    • Manufacturer:Anfarm Pharmaceuticals

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